Huntington's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Huntington's Disease, including details on genetics, causes, symptoms, treatment.

Speech and language delay are early manifestations of juvenile-onset Huntington disease.

Yoon G, Kramer J, Zanko A, Guzijan M, Lin S, Foster-Barber A, Boxer AL

Division of Medical Genetics, Department of Pediatrics, University of California, San Francisco, CA 94143-1207, USA.

The neurocognitive features of juvenile-onset Huntington disease (HD) are not well understood. We present three patients with onset of HD symptoms before age 10 years in whom speech delay was the first symptom. Speech delay predated motor symptoms by at least 2 years, and language function was consistently impaired on formal testing. Screening for speech delay is particularly important in children with a family history of HD.

Published 10 October 2006 in Neurology, 67(7): 1265-7.
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