Huntington's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Huntington's Disease, including details on genetics, causes, symptoms, treatment.

Volume 1 (2005), Issue 4 (April)

1. Reproductive decision making before and after predictive testing for Huntington's disease: an Australian perspective.
   Clin Genet, 67(5): 404-11. [Abstract] [Full-text]
2. Lentiviral gene delivery of GDNF into the striatum of R6/2 Huntington mice fails to attenuate behavioral and neuropathological changes.
   Exp Neurol, 193(1): 65-74. [Abstract] [Full-text]
3. CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model.
   J Neurochem, 93(2): 310-20. [Abstract] [Full-text]
4. Progression of structural neuropathology in preclinical Huntington's disease: a tensor based morphometry study.
   J Neurol Neurosurg Psychiatry, 76(5): 650-5. [Abstract] [Full-text]
5. A human single-chain Fv intrabody preferentially targets amino-terminal Huntingtin's fragments in striatal models of Huntington's disease.
   Neurobiol Dis, 19(1): 47-56. [Abstract] [Full-text]
6. Decreased expression of hypothalamic neuropeptides in Huntington disease transgenic mice with expanded polyglutamine-EGFP fluorescent aggregates.
   J Neurochem, 93(3): 641-53. [Abstract] [Full-text]
7. Tryptophan metabolism and oxidative stress in patients with Huntington's disease.
   J Neurochem, 93(3): 611-23. [Abstract] [Full-text]
8. RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model.
   Proc Natl Acad Sci U S A, 102(16): 5820-5. [Abstract] [Full-text]
9. Expression pattern of apoptosis-related markers in Huntington's disease.
   Acta Neuropathol (Berl), 109(3): 321-8. [Abstract] [Full-text]
10. Akt is altered in an animal model of Huntington's disease and in patients.
    Eur J Neurosci, 21(6): 1478-88. [Abstract] [Full-text]
11. The role of the striatum in rule application: the model of Huntington's disease at early stage.
    Brain, 128: 1155-67. [Abstract] [Full-text]
12. Striatal potassium channel dysfunction in Huntington's disease transgenic mice.
    J Neurophysiol, 93(5): 2565-74. [Abstract] [Full-text]
13. Intact ability to learn internal models of arm dynamics in Huntington's disease but not cerebellar degeneration.
    J Neurophysiol, 93(5): 2809-21. [Abstract] [Full-text]
14. Verification of somatic CAG repeat expansion by pre-PCR fractionation.
    J Neurosci Methods, 144(1): 11-7. [Abstract] [Full-text]
15. A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease.
    Nat Genet, 37(5): 526-31. [Abstract] [Full-text]

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