Huntington's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Huntington's Disease, including details on genetics, causes, symptoms, treatment.

Volume 1 (2005), Issue 10 (October)

1. A similar impairment in CA3 mossy fibre LTP in the R6/2 mouse model of Huntington's disease and in the complexin II knockout mouse.
   Eur J Neurosci, 22(7): 1701-12. [Abstract] [Full-text]
2. Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease.
   Hum Mol Genet, 14(20): 3065-78. [Abstract] [Full-text]
3. History of genetic disease: the molecular genetics of Huntington disease - a history.
   Nat Rev Genet, 6(10): 766-73. [Abstract] [Full-text]
4. Age at onset of Huntington disease is not modulated by the R72P variation in TP53 and the R196K variation in the gene coding for the human caspase activated DNase (hCAD).
   BMC Med Genet, 6: 35. [Abstract] [Full-text]
5. Differential impairment of spatial location memory in Huntington's disease.
   J Neurol Neurosurg Psychiatry, 76(11): 1516-9. [Abstract] [Full-text]
6. Regional white matter change in pre-symptomatic Huntington's disease: a diffusion tensor imaging study.
   Psychiatry Res, 140(1): 55-62. [Abstract] [Full-text]
7. Clinico-pathological rescue of a model mouse of Huntington's disease by siRNA.
   Neurosci Res, 53(3): 241-9. [Abstract] [Full-text]
8. Susceptibility of striatal neurons to excitotoxic injury correlates with basal levels of Bcl-2 and the induction of P53 and c-Myc immunoreactivity.
   Neurobiol Dis, 20(2): 562-73. [Abstract] [Full-text]
9. Huntingtin is cleaved by caspases in the cytoplasm and translocated to the nucleus via perinuclear sites in Huntington's disease patient lymphoblasts.
   Neurobiol Dis, 20(2): 267-74. [Abstract] [Full-text]
10. Adenosine A2A receptor dysfunction correlates with age at onset anticipation in blood platelets of subjects with Huntington's disease.
    Am J Med Genet B Neuropsychiatr Genet, 139(1): 101-5. [Abstract] [Full-text]
11. Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.
    J Neurosci, 25(43): 9932-9. [Abstract] [Full-text]

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